Antimicrobial Susceptibility Testing (AST) miniseries
Listen to these episodes:
https://idiotspodcasting.buzzsprout.com/1782416/episodes/16404166-101-ast-when-there-are-breakpoints-how-to-use-the-eucast-clinical-breakpoints-table
https://idiotspodcasting.buzzsprout.com/1782416/episodes/16404171-102-ast-when-there-are-no-breakpoints-how-to-use-the-eucast-guidance-document
Look at this episode first:
92. AST: What is Resistance anyway? (S/I/R) (1)
Definitions to understand
When are there ARE breakpoints
The first and very important question is, when are there no breakpoints in the EUCAST breakpoint tables?
Where to find clinical breakpoints:
EUCAST clinical breakpoint tables (updated yearly)
CLSI main other option (not discussed further here)
Using the EUCAST clinical breakpoints table (S/I/R + “-” + “IE”)
There are three main options in the breakpoints table
- Breakpoint is listed
- Some breakpoints are “bracketed”
- Some are specified for specific indications
- Some have “notes” applied
- “-”
- “IE”
We’ve worked through these features with examples below