Thank you BIA. I’m here to talk to you today

about Iversen et al. It came out quite a while

ago in January 2019

challenging the dogmas of oral versus IV

But before I vent my Venflon-hating, tablet-loving spleen

first I feel I need to step right back & set the scene.

The year was 1945, when accepting the Nobel Prize

was Alexander Fleming, the greatest Scot who’s not alive

Back then endocarditis, well, it wasn’t all that great

Pre-antibiotics it’s a nought percent survival rate

And that led some doctors to parlay and hypothecate

that a course of antibiotics might set these unlucky patients straight.

First they tried sulphonamides, cousins of cotrimoxazole

Or at least one half of it, you can look it up, but damn it all

if the bug/drug MICs were simply far too high