https://doi.org/10.1016/s0140-6736(21)00313-5

Background

PICO

Inclusion

Exclusion

Methods

Statistics

Outcomes

Primary

Cure @15d

• Apyrexia
• • Improved/resolved clinical signs/symptoms
    • Cough frequency/severity
    • Sputum production
    • Dyspnoea
    • Crackles
• • No additional ABx Rx for any reason

Secondary

• Cure @30d
• Adverse events
• CAP score @ D0,3,8,15,30
• Hospital LoS by D15
• Compliance @ D15